503A · CompoundedIllustration only. Actual medication will vary.Women's Health · Topical estrogen
Estradiol
Cream
A topical estradiol cream in a metered unodose tube. 0.1% (30 g) or 0.2% (42 g).
Your Plan Options
Estradiol 0.1%
Unodose · 30 g tube · 30-day supply
$139 /mo
Estradiol 0.1%
Unodose · 30 g tube · 90-day supply
$379 /3 mo
Best value
Estradiol 0.2%
2 mg/g · Unodose · 42 g tube · 30-day supply
$159 /mo
Estradiol 0.2%
2 mg/g · Unodose · 42 g tube · 90-day supply
$419 /3 mo
Best value
No charge until a provider prescribes. Prescription required.
Clinical information
What this is, in plain language.
Estradiol cream delivers estrogen through the skin from a metered unodose dispenser. It is prepared by a licensed 503A compounding pharmacy and dispensed only when a licensed provider determines it is clinically appropriate.
Active ingredients
Estradiol 0.1% or 0.2% (2 mg/g).
Mechanism
Supplements estrogen levels that decline around menopause.
Administration
Measured dose applied to the skin daily, as directed by your prescriber.
Who it is for
Adults experiencing menopause symptoms, when clinically appropriate.
Common effects
Breast tenderness, spotting, bloating, headache. Discuss full risks, including blood clots and stroke, with your provider.
Important safety & compliance information
Compounded estradiol cream is not FDA-approved. It is prepared by a licensed 503A compounding pharmacy and is descriptive only — it is not a branded drug. Product imagery shown here is illustration only; actual medication is dispensed in a pharmacy-labeled container and will vary in appearance. A prescription is required and is issued only when a licensed provider determines treatment is clinically appropriate. This page is not medical advice. Discuss benefits, risks and side effects with your provider.