503A · CompoundedIllustration only. Actual medication will vary.Women's Health · Local estrogen
Estradiol
Vaginal Cream
A low-dose local estrogen cream, available on its own or with vitamin E. 30 g tube.
Your Plan Options
Estradiol 0.01%
0.1 mg/g · 30 g tube · 30-day supply
$119 /mo
Estradiol 0.01%
0.1 mg/g · 30 g tube · 90-day supply
$319 /3 mo
Best value
Estradiol 0.01% / Vitamin E 1%
30 g tube · 30-day supply
$129 /mo
Estradiol 0.01% / Vitamin E 1%
30 g tube · 90-day supply
$349 /3 mo
Best value
No charge until a provider prescribes. Prescription required.
Clinical information
What this is, in plain language.
Estradiol vaginal cream delivers a low dose of estrogen locally. It is prepared by a licensed 503A compounding pharmacy and dispensed only when a licensed provider determines it is clinically appropriate.
Active ingredients
Estradiol 0.01% (0.1 mg/g); optional vitamin E 1%.
Mechanism
Local estrogen supporting vaginal tissue affected by lower estrogen levels.
Administration
Applied vaginally on a schedule set by your prescriber.
Who it is for
Adults with vaginal dryness or discomfort related to menopause, when clinically appropriate.
Common effects
Local irritation, spotting, breast tenderness. Discuss full risks with your provider.
Important safety & compliance information
Compounded estradiol vaginal cream is not FDA-approved. It is prepared by a licensed 503A compounding pharmacy and is descriptive only — it is not a branded drug. Product imagery shown here is illustration only; actual medication is dispensed in a pharmacy-labeled container and will vary in appearance. A prescription is required and is issued only when a licensed provider determines treatment is clinically appropriate. This page is not medical advice. Discuss benefits, risks and side effects with your provider.